| Election Name: | 1980 United States Senate election in Missouri |
| Country: | Missouri |
| Type: | Presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in Missouri |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in Missouri |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | File:ThomasEagleton (3x4 a).jpg |
| Nominee1: | Thomas Eagleton |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 1,074,859 |
| Percentage1: | 52.00% |
| Nominee2: | Gene McNary |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 985,399 |
| Percentage2: | 47.67% |
| Map Size: | 275px |
| U.S. Senator | |
| Before Election: | Thomas Eagleton |
| Before Party: | Democratic Party (United States) |
| After Election: | Thomas Eagleton |
| After Party: | Democratic Party (United States) |
The 1980 United States Senate election in Missouri was held on November 4, 1980. Incumbent Senator Thomas Eagleton defeated Republican nominee Gene McNary with 52.00% of the vote. As of 2024, this is the last time the Democrats won the Class 3 Senate seat in Missouri.
Primary elections were held on August 5, 1980.[1]
Major party candidates
Other candidates