| Election Name: | 1988 United States Senate election in Massachusetts |
| Country: | Massachusetts |
| Type: | presidential |
| Ongoing: | noh |
| Previous Election: | 1982 United States Senate election in Massachusetts |
| Previous Year: | 1982 |
| Next Election: | 1994 United States Senate election in Massachusetts |
| Next Year: | 1994 |
| Election Date: | November 8, 1988 |
| Image1: | TedKennedy.png |
| Nominee1: | Ted Kennedy |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 1,693,344 |
| Percentage1: | 64.97% |
| Nominee2: | Joe Malone |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 884,267 |
| Percentage2: | 33.93% |
| Map Size: | 250px |
| U.S. Senator | |
| Before Election: | Ted Kennedy |
| Before Party: | Democratic Party (United States) |
| After Election: | Ted Kennedy |
| After Party: | Democratic Party (United States) |
The 1988 United States Senate election in Massachusetts was held on November 8, 1988. Incumbent Democratic U.S. Senator Ted Kennedy won re-election to his sixth (his fifth full) term.