| Election Name: | 1988 United States Senate election in Hawaii |
| Country: | Hawaii |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1982 United States Senate election in Hawaii |
| Previous Year: | 1982 |
| Next Election: | 1990 United States Senate special election in Hawaii |
| Next Year: | 1990 (special) |
| Election Date: | November 8, 1988 |
| Image1: | Spark Matsunaga, 1986.jpg |
| Nominee1: | Spark Matsunaga |
| Party1: | Democratic Party (United States) |
| Popular Vote1: | 247,941 |
| Percentage1: | 76.55% |
| Nominee2: | Maria Hustace |
| Party2: | Republican Party (United States) |
| Popular Vote2: | 66,987 |
| Percentage2: | 20.68% |
| Map Size: | 300px |
| U.S. Senator | |
| Before Election: | Spark Matsunaga |
| Before Party: | Democratic Party (United States) |
| After Election: | Spark Matsunaga |
| After Party: | Democratic Party (United States) |
The 1988 United States Senate election in Hawaii took place on November 8, 1988. Incumbent Democratic U.S. Senator Spark Matsunaga won re-election to a third and final term.[1]
On April 15, 1990, Senator Matsunaga died of bone cancer, leading Governor John Waihe'e to appoint U.S. Representative from Hawaii's 2nd district Daniel Akaka to fill the seat. Akaka ran in the 1990 special election to fill out the remainder of the term, but won for his full term.