| Election Name: | 1980 United States Senate election in Arizona |
| Country: | Arizona |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 1974 United States Senate election in Arizona |
| Previous Year: | 1974 |
| Next Election: | 1986 United States Senate election in Arizona |
| Next Year: | 1986 |
| Election Date: | November 4, 1980 |
| Image1: | File:Barry Goldwater.jpg |
| Nominee1: | Barry Goldwater |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 432,371 |
| Percentage1: | 49.46% |
| Nominee2: | Bill Schulz |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 422,972 |
| Percentage2: | 48.38% |
| Map Size: | 210px |
| U.S. Senator | |
| Before Election: | Barry Goldwater |
| Before Party: | Republican Party (United States) |
| After Election: | Barry Goldwater |
| After Party: | Republican Party (United States) |
The 1980 United States Senate election in Arizona took place on November 4, 1980. Incumbent Republican Senator Barry Goldwater decided to run for reelection to a third consecutive term, after returning to the Senate in 1968 following his failed presidential run in 1964 against Lyndon B. Johnson. Despite Republican presidential nominee Ronald Reagan's landslide win in Arizona, Goldwater defeated Democratic Party nominee Bill Schulz in the general election by a narrow margin, which later caused Goldwater to decide against running for reelection to a fourth consecutive term. Goldwater won only three counties, including Maricopa County.