| District | Incumbent | Party | First elected | Result | Candidates | ||||
|---|---|---|---|---|---|---|---|---|---|
| Thomas Pinckney | Federalist | 1797 (Special) | Incumbent re-elected. | nowrap | √ Thomas Pinckney (Federalist) 100% | ||||
| John Rutledge, Jr. | Federalist | 1796 | Incumbent re-elected. | nowrap | √ John Rutledge, Jr. (Federalist) 65.6% Pierce Butler (Democratic-Republican) 34.4% | ||||
| Lemuel Benton | Democratic- Republican | 1793 | Incumbent lost re-election. New member elected. Federalist gain. | nowrap | √ Benjamin Huger (Federalist) 41.9% Lemuel Benton (Democratic-Republican) 32.4% Tristam Thomas (Federalist) 22.2% William Thomas (Democratic-Republican) 2.0% Joseph Blyth (Democratic-Republican) 1.6% | ||||
| Thomas Sumter | Democratic- Republican | 1796 | Incumbent re-elected. | nowrap | √ Thomas Sumter (Democratic-Republican) 64.6% Richard Winn (Federalist) 35.4% | ||||
| Robert Goodloe Harper | Federalist | 1794 | Incumbent re-elected. | nowrap | √ Robert Goodloe Harper (Federalist) 65.3% William Butler (Democratic-Republican) 34.7% | ||||
| William Smith | Democratic- Republican | 1796 | Incumbent lost re-election. New member elected. Federalist gain. | nowrap | √ Abraham Nott (Federalist) 43.8% William Smith (Democratic-Republican) 43.2% William Hill (Federalist) 13.0% |