Only one of the five South Carolina incumbents were re-elected.
Electoral data are only available for the 1st and 5th district of South Carolina's 6 districts at the time of the elections of 1794.
| District | Incumbent | Party | First elected | Result | Candidates | ||||
|---|---|---|---|---|---|---|---|---|---|
| William L. Smith | Pro-Administration | 1788 | Incumbent re-elected to a new party. Federalist gain. | nowrap | √ William L. Smith (Federalist) 51.7% John Rutledge, Jr. (Federalist) 37.3% Thomas Tucker 11.0% | ||||
| New seat | New member elected. Democratic-Republican gain. Winner declined to serve and a special election was held to fill the resulting vacancy, electing Wade Hampton (Democratic-Republican). | nowrap | √ Robert Barnwell[1] | ||||||
| Lemuel Benton | Anti-Administration | 1793 | Incumbent re-elected to a new party. Democratic-Republican gain. | nowrap | √ Lemuel Benton (Democratic-Republican) | ||||
| Richard Winn | Anti-Administration | 1793 | Incumbent re-elected to a new party. Democratic-Republican gain. | nowrap | √ Richard Winn (Democratic-Republican) | ||||
| Alexander Gillon | Anti-Administration | 1793 | Incumbent died October 6, 1794. New member elected. Federalist gain. Winner of general election was also elected to finish Gillon's term, see above. | √ Robert Goodloe Harper (Federalist) 58.3% John Hunter (Democratic-Republican) 41.7% | |||||
| Anti-Administration | 1793 | Incumbent lost re-election. Anti-Administration loss. | |||||||
| Andrew Pickens | Anti-Administration | 1793 | Unknown if incumbent retired or lost re-election. Democratic-Republican gain. | nowrap | √ Samuel Earle (Democratic-Republican) | ||||