The 1810 census revealed dramatic population growth in Ohio since 1800, resulting in its representation increasing from a single Representative to six, resulting in the State being broken up into 6 districts, abolishing the . Jeremiah Morrow (Democratic-Republican), who had served since Ohio achieved statehood in 1803, retired to run for U.S. Senator, so that all six seats were open. Its elections were held October 13, 1812.
| District | Incumbent | This race | ||||||
|---|---|---|---|---|---|---|---|---|
| Representative | Party | First elected | Results | Candidates | ||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | √ John McLean (Democratic-Republican) 71.3% Ethan Stone (Federalist) 16.6% John Bigger (Federalist) 10.7% Othneil Looker (Democratic-Republican) 1.4% | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | √ John Alexander (Democratic-Republican) 38.5% John W. Campbell (Democratic-Republican) 35.6% Thomas Morris (Democratic-Republican) 25.9% | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. Successor resigned April 5, 1813, after the new Congress began but before it first met, leading to a special election. | nowrap | √ Duncan McArthur (Democratic-Republican) 99.9% | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | √ James Caldwell (Democratic-Republican) 51.5% Bezaleel Wells (Federalist) 43.1% James Pritchard (Democratic-Republican) 5.4% | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | √ James Kilbourne (Democratic-Republican) 24.5% Robert J. Slaughter 23.3% Robert Cloud 17.3% Joseph Foos 13.2% William W. Irvin 12.5% Joseph H. Crane 8.9% | |||||
| None (District created) | New seat. New member elected. Democratic-Republican gain. | nowrap | √ John S. Edwards (Federalist) 60.0% Reasin Beall (Democratic-Republican) 38.4% | |||||