| Election Name: | 2010 United States House of Representatives election in Wyoming's at-large district |
| Country: | Wyoming |
| Type: | presidential |
| Ongoing: | no |
| Previous Election: | 2008 United States House of Representatives election in Wyoming |
| Previous Year: | 2008 |
| Next Election: | 2012 United States House of Representatives election in Wyoming |
| Next Year: | 2012 |
| Election Date: | November 2, 2010 |
| Nominee1: | Cynthia Lummis |
| Party1: | Republican Party (United States) |
| Popular Vote1: | 131,661 |
| Percentage1: | 70.42% |
| Nominee2: | David Wendt |
| Party2: | Democratic Party (United States) |
| Popular Vote2: | 45,768 |
| Percentage2: | 24.48% |
| Map Size: | 250px |
| U.S. Representative | |
| Before Election: | Cynthia Lummis |
| Before Party: | Republican Party (United States) |
| After Election: | Cynthia Lummis |
| After Party: | Republican Party (United States) |
The 2010 United States House of Representatives election in Wyoming was held on November 2, 2010, and determined who would represent the state of Wyoming in the United States House of Representatives. Representatives are elected for two-year terms; the elected served in Congress from 2011 to 2013. The election coincided with the 2010 midterm elections.
Wyoming has one seat in the House, apportioned according to the 2000 United States census. Its 2008-2010 congressional House delegation consisted of one Republican.
| width='150' | Poll Source | width='150' | Dates Administered | width='130' | Cynthia Lummis (R) | width='130' | David Wendt (D) |
|---|---|---|---|---|---|---|---|
| Rasmussen Reports[1] | September 30, 2010 | align=center | 61% | 29% | |||
| Mason-Dixon[2] | July 26–28, 2010 | align=center | 59% | 29% |