| Post: | Ambassador |
| Body: | the United States to Iran |
| Insignia: | US Department of State official seal.svg |
| Insigniasize: | 120px |
| Insigniacaption: | Seal of the United States Department of State |
| Incumbent: | None |
| Nominator: | The President of the United States |
| Inaugural: | Leland Burnette Morris |
| Formation: | 1944 |
| Abolished: | 1979 |
Prior to 1944, Iran was not served by a United States ambassador; instead, a diplomatic minister was sent. The first ambassador was named in 1944.
After the Iran hostage crisis in 1979, the United States terminated diplomatic relations with the Iranian government, therefore no ambassadors have since been appointed. The United States government has since then been represented in Iran by the United States Interests Section of the Embassy of Switzerland in Tehran.
This is a list of United States ambassadors and other heads of diplomatic missions to Iran.