| Clubname: | Deportes Santa Cruz |
| Fullname: | Club de Deportes Santa Cruz |
| Nickname: | Santacruzanos |
| Founded: | May 25, 1913 |
| Ground: | Estadio Municipal Joaquín Muñoz García Santa Cruz, Chile |
| Capacity: | 5,000 |
| Chairman: | Cristian San Miguel |
| Manager: | Osvaldo Hurtado |
| League: | Primera B |
| Season: | 2023 |
| Position: | 13th |
| Leftarm1: | FFFFFF |
| Body1: | FFFFFF |
| Rightarm1: | FFFFFF |
| Shorts1: | FFFFFF |
| Socks1: | FFFFFF |
| Leftarm2: | 000099 |
| Body2: | 000099 |
| Rightarm2: | 000099 |
| Shorts2: | 000099 |
| Socks2: | 000099 |
Club de Deportes Santa Cruz is a football club based in Santa Cruz, Chile. The club currently plays in the Chilean Primera Division B, the second tier of Chilean football. The club was founded on May 25, 1913 as Unión Comercio. In 1983 the club was rechristened Unión Santa Cruz and a second time in 1998 to the current club name.
2018
1991
2012