These hits topped the Ultratop 50 in 2001.[1]
| Date | Artist | Title | |
|---|---|---|---|
| January 6 | Big Brother De Bewoners & Walter Grootaers | "Een brief voor Kerstmis" | |
| January 13 | "Wêr bisto" | ||
| January 20 | |||
| January 27 | |||
| February 3 | "Can't Fight the Moonlight" | ||
| February 10 | |||
| February 17 | "La Passion" | ||
| February 24 | |||
| March 3 | |||
| March 10 | |||
| March 17 | |||
| March 24 | "It Wasn't Me" | ||
| March 31 | |||
| April 7 | |||
| April 14 | |||
| April 21 | "Teenage Dirtbag" | ||
| April 28 | |||
| May 5 | |||
| May 12 | Vanda Vanda | "Sunshine After the Rain" | |
| May 19 | |||
| May 26 | |||
| June 2 | "It's Raining Men" | ||
| June 9 | |||
| June 16 | |||
| June 23 | |||
| June 30 | "Angel" | ||
| July 7 | |||
| July 14 | |||
| July 21 | |||
| July 28 | "Tele-Romeo" / "Blub, ik ben een vis" | ||
| August 4 | |||
| August 11 | |||
| August 18 | |||
| August 25 | |||
| September 1 | |||
| September 8 | "Eternal Flame" | ||
| September 15 | "Let Me Blow Ya Mind" | ||
| September 22 | |||
| September 29 | "Fallin'" | ||
| October 6 | "Can't Get You Out of My Head" | ||
| October 13 | |||
| October 20 | |||
| October 27 | |||
| November 3 | |||
| November 10 | |||
| November 17 | "Because I Got High" | ||
| November 24 | |||
| December 1 | |||
| December 8 | |||
| December 15 | |||
| December 22 | |||
| December 29 | "What If" |