Post-war, she was decommissioned and ended up in the hands of the Dominican Navy as Juan Pablo Duarte in 1947, but ran aground and taken out of service in 1949. In 1950 she was sold to Puerto Rican engineer Félix Benítez as a private yacht. The ship was broken up in 1959.
Natchez was laid down on 16 March 1942 by Canadian Vickers Ltd., Montreal, Quebec, Canada as HMS Annan, later designated as HMCS Annan.Due to a lack of American patrol vessels she was transferred to the U.S. Navy on 20 July 1942. Launched on 12 September 1942, she was named USS Natchez (PG-102) on 8 October 1942 and commissioned at Ottawa, Ontario on 16 December 1942.
Natchez sailed under escort to Boston, Massachusetts, arriving at the Boston Navy Yard 16 January 1943 for fitting out. On 1 March she reported for duty to Commander Eastern Sea Frontier and was assigned escort duty for merchant convoys between Cuba and New York City. Natchez was redesignated as PF-2 on 15 April 1943.
On 4 December, Cuban freighter was reported missing from her convoy off the southern Atlantic coast. Natchez with several other patrol vessels, was dispatched to the scene, guided by homing signals from Navy blimps. Natchez found only three survivors who reported that their ship had been torpedoed and had sunk before they could notify the convoy commander.
Through 1944 Natchez escorted convoys and performed anti-submarine patrol duties. While on convoy duty 29 April 1945, she simultaneously received a sonar contact and sighted the snorkel of German submarine U-879, 98miles east of Cape Henry, Virginia. Launching an immediate attack, she was quickly joined by three destroyer escorts:, and . Hedgehogs and depth charges were used as the four vessels sought to trap the enemy submarine. Finally contact was lost and a large quantity of oil was seen to rise to the surface, indicating destruction of the U-boat.
At the end of the war Natchez was still patrolling in the Atlantic. She returned to Charleston, South Carolina on 29 June 1945 for inactivation and disposal.
She was delivered to the Maritime Commission, 19 November 1945 for disposal. She was sold, 29 July 1947 to Louis Moore of Miami, Florida then resold on 19 March 1948 to the Dominican Republic as Juan Pablo Duarte (F102). She ran aground at Puerto Plata, Dominican Republic in November 1949 and taken out of service due to damage. She was then sold to Félix Benítez, a Puerto Rican engineer, who repaired her and converted her to his personal yacht Moineau. She was broken up in 1959.