The second ship to be so named by the Navy, Huntsville was laid down under U.S. Maritime Commission contract as Knox Victory by Oregon Shipbuilding Corporation, Portland, Oregon, 2 March 1945; launched 13 April 1945; sponsored by Mrs. Charles B. Gilbert; and delivered to the War Shipping Administration (WSA) 11 May 1945 for charter operated by Olympic Steamship Company.
During the remainder of the war she operated as a merchant ship under charter to Olympic Steamship Company, and she continued merchant service under bareboat charters from the Maritime Commission and the Maritime Administration until 1958 when she entered the National Defense Reserve Fleet at Olympia, Washington.
Knox Victory was acquired by the Navy from the Maritime Administration 11 August 1960 and assigned to the Military Sea Transportation Service (MSTS). She was renamed Huntsville and designated T-AGM-7, a missile range instrumentation ship, 27 November.
After conversion to a special projects ship by Triple "A" Machine Shop, Inc., San Francisco, California, Huntsville began duty as a range tracking ship in 1961.
Crewed by civilians, Huntsville operated out of Port Hueneme, California, and Honolulu, Hawaii, while assigned to special duties in the Pacific Ocean. During the next 4 years she made intermittent "on station" patrols in the Central Pacific, extending from the coast of Mexico to Wake Island and the Marshall Islands. She continued these patrols, which contributed mightily on America's space programs, until the spring of 1965; then she entered Avondale Shipyards, Inc., Westwego, Louisiana, 2 June 1965 for conversion, completed 30 October 1966.
Two other ships were reconfigured in to this new class, Watertown-class missile range instrumentation ship, the USNS Watertown (T-AGM-6) and the USNS Wheeling (T-AGM-8).
In June 1967 Huntsville returned to the Pacific, where she operated with Watertown (T-AGM-6). As an improved sea-based tracking station, she provided an important link in communications during the scheduled "Apollo" moon shots, which were designed to send American astronauts to the moon and back.
One of the last missions for the Huntsville was in support of US surveillance of nuclear testing in the South Pacific. Huntsville spent approximately 90 days between June and September 1974 on that mission, most of it in the vicinity of Mururoa Atoll.
The following paragraph appeared in the Stanford Research Institute Alumni Newsletter in 2010 in an article by Walter Jaye entitled Adventures at Sea in the South Pacific.
"The Conclusion of the Missions:
In 1974, the third and final year of these operations, the ship used was the USNS Huntsville (see photo). The use of helicopters was dropped, and instead remotely piloted vehicles were launched from the Huntsville."
Huntsville was placed out of service on an unknown date, and was struck from the Navy List on 8 November 1974. She was placed in the National Defense Reserve Fleet and eventually sold by MARAD on 17 July 1995. Her subsequent fate is not known.