UNC93B1 explained

Unc-93 homolog B1 (C. elegans), also known as UNC93B1, is a protein which in humans is encoded by the UNC93B1 gene.^{[1] [2]}

Function

This gene encodes a protein with similarity to the Caenorhabditis elegans unc93 protein. The Unc93 protein is involved in the regulation or coordination of muscle contraction in the worm.^[1]

Further reading

• Andersson B, Wentland MA, Ricafrente JY, etal . A "double adaptor" method for improved shotgun library construction . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 .
• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Yu W, Andersson B, Worley KC, etal . Large-Scale Concatenation cDNA Sequencing . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 .
• Toward a complete human genome sequence . Genome Res. . 8 . 11 . 1097–108 . 1999 . 9847074 . 10.1101/gr.8.11.1097. free . Sanger Centre . The . Washington University Genome Sequencing Cente . The .
• Kashuba VI, Protopopov AI, Kvasha SM, etal . hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein . Gene . 283 . 1–2 . 209–17 . 2002 . 11867227 . 10.1016/S0378-1119(01)00856-3 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Arnlöv J, Sundström J, Lind L, etal . hUNC-93B1, a novel gene mainly expressed in the heart, is related to left ventricular diastolic function, heart failure morbidity and mortality in elderly men . Eur. J. Heart Fail. . 7 . 6 . 958–65 . 2006 . 16111919 . 10.1016/j.ejheart.2004.06.009 . 22339419 . free .
• Taylor TD, Noguchi H, Totoki Y, etal . Human chromosome 11 DNA sequence and analysis including novel gene identification . Nature . 440 . 7083 . 497–500 . 2006 . 16554811 . 10.1038/nature04632 . 2006Natur.440..497T . free .
• Casrouge A, Zhang SY, Eidenschenk C, etal . Herpes simplex virus encephalitis in human UNC-93B deficiency . Science . 314 . 5797 . 308–12 . 2006 . 16973841 . 10.1126/science.1128346 . 2006Sci...314..308C . 12501759 . free .

Notes and References

1. Web site: Entrez Gene: UNC93B1 unc-93 homolog B1 (C. elegans).
2. Kashuba VI, Protopopov AI, Kvasha SM, Gizatullin RZ, Wahlestedt C, Kisselev LL, Klein G, Zabarovsky ER . hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein . Gene . 283 . 1–2 . 209–17 . January 2002 . 11867227 . 10.1016/S0378-1119(01)00856-3 .