UDP-N-acetylglucosamine—undecaprenyl-phosphate N-acetylglucosaminephosphotransferase explained

UDP-N-acetylglucosamine—undecaprenyl-phosphate N-acetylglucosaminephosphotransferase
Ec Number:	2.7.8.33

(, WecA, WecA transferase, , , GPT, TagO, , ) is an enzyme with systematic name .^{[1] [2] [3] [4]} This enzyme catalyses the following chemical reaction

\rightleftharpoons UMP +

This enzyme catalyses the synthesis of .

Notes and References

1. Al-Dabbagh B, Mengin-Lecreulx D, Bouhss A . Purification and characterization of the bacterial UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase WecA . Journal of Bacteriology . 190 . 21 . 7141–6 . November 2008 . 18723618 . 2580700 . 10.1128/jb.00676-08 .
2. Lehrer J, Vigeant KA, Tatar LD, Valvano MA . Functional characterization and membrane topology of Escherichia coli WecA, a sugar-phosphate transferase initiating the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide . Journal of Bacteriology . 189 . 7 . 2618–28 . April 2007 . 17237164 . 1855806 . 10.1128/jb.01905-06 .
3. Rush JS, Rick PD, Waechter CJ . Polyisoprenyl phosphate specificity of UDP-GlcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase from E.coli . Glycobiology . 7 . 2 . 315–22 . March 1997 . 9134438 . 10.1093/glycob/7.2.315 . free .
4. Soldo B, Lazarevic V, Karamata D . tagO is involved in the synthesis of all anionic cell-wall polymers in Bacillus subtilis 168 . Microbiology . 148 . Pt 7 . 2079–87 . July 2002 . 12101296 . 10.1099/00221287-148-7-2079 . free .