UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase explained

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
Ec Number:	2.6.1.92

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase (PseC) is an enzyme with systematic name UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine:2-oxoglutarate aminotransferase.^{[1] [2]} This enzyme catalyses the following chemical reaction

\rightleftharpoons UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate

This enzyme is a pyridoxal-phosphate protein.

Notes and References

1. Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young NM, Dick S, Wakarchuk WW, Brisson JR, Logan SM . Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways . The Journal of Biological Chemistry . 281 . 2 . 723–32 . January 2006 . 16286454 . 10.1074/jbc.m511021200 . free .
2. Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S, Wakarchuk WW, Young NM . Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of pseudaminic acid, an essential flagellar modification in Helicobacter pylori . The Journal of Biological Chemistry . 281 . 13 . 8907–16 . March 2006 . 16421095 . 10.1074/jbc.m512987200 . free .