| Host: | University of the Philippines |
| UAAP Season 78 Football | |
| Higherseed: | |
| Higherseed Game1: | 4 |
| Higherseed Series: | 1 |
| Lowerseed Game1: | 1 |
| Lowerseed Series: | 0 |
| Arena: | Rizal Memorial Stadium |
| Mvp: | Kintaro Miyagi |
| Coach: | Anto Gonzales |
| Semis: | |
| Network: | ABS-CBN Sports+Action |
| Whigherseed Game1: | 1 |
| Whigherseed Series: | 0 |
| Wlowerseed: | |
| Wlowerseed Game1: | 2 |
| Wlowerseed Series: | 1 |
| Warena: | Rizal Memorial Stadium |
| Wmvp: | BG Sta. Clara |
| Wcoach: | Anto Gonzales |
| Wnetwork: | ABS-CBN Sports+Action |
| Jhigherseed: | |
| Jhigherseed Game1: | 6 |
| Jhigherseed Series: | 1 |
| Jlowerseed Game1: | 1 |
| Jlowerseed Series: | 0 |
| Jduration: | February 7, 2016 |
| Prevlink: | UAAP Season 77 football tournaments |
| Prev: | 77 |
| Seasonlink: | UAAP Season 78 |
| Year: | 2015–16 |
| Nextlink: | UAAP Season 79 football tournaments |
| Next: | 79 |
The UAAP Season 78 seniors division football tournament started on February 7, 2016, following the shift in the start of the league. The tournament opened at Emperador McKinley Hill Stadium in Fort Bonifacio, Taguig City. Other games were held at the Moro Lorenzo Football Field of Ateneo de Manila University in Katipunan Ave., Loyola Heights, Quezon City. Ateneo was the tournament host.
The men's and women's Final matches happened on May 5, 2016, which is exactly eight months after the start of the Season last September 5, 2015. The championship games also served as the last ones for the Season, making football the final event.