| State: | TX |
| Type: | US-Alt |
| Route: | 281 |
| Map Custom: | yes |
| Map Notes: | Alt. US 281 highlighted in red |
| Spur Type: | US |
| Spur Of: | 281 |
| Length Mi: | 16.719 |
| Established: | 1982 |
| Direction A: | South |
| Terminus A: | near Whitsett |
| Direction B: | North |
| Terminus B: | near Campbellton |
| Previous Type: | US |
| Previous Route: | 281 |
| Next Type: | US |
| Next Route: | 283 |
Alternate U.S. Highway 281 (Alt. US 281) is a loop of the U.S. Highway System. The highway serves the small communities of Whitsett and Campbellton, about 45miles southeast of San Antonio in the state of Texas.
Alt. US 281 begins at an interchange with Interstate 37/US 281 (I-37/US 281) about 6miles southeast of Whitsett; the same interchange also provides access to Farm to Market Road 2049 (FM 2049). The highway enters the town and crosses FM 99 before leaving. Just north of Whitsett, the highway turns from a northwesterly direction to a more northward one. The highway passes by many farms before entering Atascosa County. After the intersection with FM 1099, the highway enters Campbellton. Alt. US 281 is concurrent with FM 791 through the town before separating just north of the city limits. About a mile to the north of here, the highway crosses FM 140. Alt. US 281 reaches its northern terminus at another interchange with I-37/US 281 about NaNmiles north of Campbellton.
The highway was created in 1982 when US 281 was re-rerouted a few miles to the east onto Interstate 37. The old alignment of US 281 through Whitsett and Campbellton was then resigned as Alt. US 281.[1] [2]