| Clubname: | Itala San Marco Gradisca |
| Fullname: | Associazione Sportiva Dilettantistica Itala San Marco Gradisca |
| Founded: | 1919 2010 (refounded) |
| Capacity: | 4,000 |
| League: | Eccellenza Friuli – Venezia Giulia |
| Position: | Serie D/C, 18th |
| Pattern B1: | _dkbluebow |
| Body1: | gggggg |
| Leftarm1: | ffffff |
| Rightarm1: | ffffff |
| Shorts1: | ffffff |
| Socks1: | ffffff |
| Pattern B2: | _bowondkblue |
| Body2: | fff |
| Leftarm2: | 00008B |
| Rightarm2: | 00008B |
| Shorts2: | 00008B |
| Socks2: | 00008B |
Associazione Sportiva Dilettantistica Itala San Marco Gradisca (usually abbreviated to I.S.M. Gradisca) is an Italian association football club located in Gradisca d'Isonzo, Friuli-Venezia Giulia. Currently it plays in Prima Categoria, the 7h tier of Italian football pyramid.
A.S.D. Itala San Mrco Gradisca was founded in 1919 as Società Sportiva Itala di Gradisca.
In 1978 the club was renamed U.S. Itala San Marco and played in Lega Pro Seconda Divisione, after having been crowned as Serie D/C winners in 2007–08.[1]
Following its withdrawal at the end of the 2009–10 Lega Pro Seconda Divisione season, the club was forced out of business.
In the summer of 2010, a new team with the current denomination was formed and was promoted from Eccellenza Friuli – Venezia Giulia to Serie D at the end of the 2010–11 season. In the season 2011–12 it was relegated to Eccellenza.
The team's colours are white and dark blue.