Turnip crinkle virus (TCV) repressor of minus strand synthesis H5 explained

Turnip crinkle virus (TCV) repressor of minus strand synthesis H5
Symbol:	TCV_H5
Rfam:	RF00500
Rna Type:	Cis-reg
Tax Domain:	Viruses

The TCV hairpin 5 (H5) is an RNA element found in the turnip crinkle virus. This RNA element is composed of a stem-loop that contains a large symmetrical internal loop (LSL). H5 can repress minus-strand synthesis when the 3' side of the LSL pairs with the 4 bases at the 3'-terminus of the RNA(GCCC-OH).^{[1] [2]}

See also

• Turnip crinkle virus (TCV) core promoter hairpin (Pr)
• Turnip crinkle virus (TCV) hairpin H4

Notes and References

1. McCormack JC, Simon AE . Biased hypermutagenesis associated with mutations in an untranslated hairpin of an RNA virus . Journal of Virology . 78 . 14 . 7813–7817 . July 2004 . 15220455 . 434097 . 10.1128/JVI.78.14.7813-7817.2004 .
2. Zhang G, Zhang J, Simon AE . Repression and derepression of minus-strand synthesis in a plus-strand RNA virus replicon . Journal of Virology . 78 . 14 . 7619–7633 . July 2004 . 15220437 . 434078 . 10.1128/JVI.78.14.7619-7633.2004 .