| Tufillo | |
| Official Name: | Comune di Tufillo |
| Coordinates: | 41.9167°N 51°W |
| Province: | (CH) |
| Area Total Km2: | 21 |
| Population Footnotes: | [1] |
| Population Total: | 508 |
| Population As Of: | 1 January 2007 |
| Population Demonym: | Tufillesi |
| Elevation M: | 578 |
| Saint: | San Vito Santa Giusta |
| Day: | 15 June |
| Postal Code: | 66050 |
| Area Code: | 0873 |
| Istat: | 069097 |
| Frazioni: | Celenza sul Trigno, Dogliola, Mafalda (CB), Montemitro (CB), Palmoli, San Felice del Molise (CB) |
Tufillo (Abruzzese: Neapolitan: Tufìlle, Neapolitan: Tufùlle) is a comune and town in the Province of Chieti in the Abruzzo region of Italy. It has a population of approximately 508.