| Tsirku River | |
| Map Size: | 300 |
| Pushpin Map: | USA Alaska |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of the mouth of the Tsirku River in Alaska |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Alaska |
| Subdivision Type4: | Borough |
| Subdivision Name4: | Haines |
| Length: | 25miles[1] |
| Source1: | Tsirku Glacier |
| Source1 Location: | north slope of Takhinsha Mountains |
| Source1 Coordinates: | 59.2972°N -136.4153°W |
| Source1 Elevation: | 1460feet[2] |
| Mouth: | Chilkat River |
| Mouth Location: | Klukwan, 21miles southwest of Skagway, St. Elias Mountains |
| Mouth Coordinates: | 59.3906°N -135.87°W[3] |
| Mouth Elevation: | 56feet |
The Tsirku River is a glacier-fed stream in Southeast Alaska near the town of Haines in the U.S. state of Alaska. The river's source is found at the Tsirku Glacier, a large, sprawling ice mass at the border of Alaska and the Canadian province of British Columbia. The river ends in a 40NaN0 wide delta near the Tlingit village of Klukwan. While many of the feeding glaciers are primarily in British Columbia, the river course lies entirely in Alaska.
After the Klehini River, the Tsirku River is the second largest tributary of the Chilkat River.