| Trombudo River | |
| Source1 Location: | Santa Catarina state |
| Mouth: | Itajaí do Oeste River |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Trombudo River is a river of Santa Catarina state in southeastern Brazil.
It rises in the municipality of Agrolândia, runs through it in a south-north direction to the center of the municipality of Trombudo Central and then runs in a southwest-northeast direction through Agronômica and flows into the Itajaí do Oeste River on the border between the municipalities of Agronômica, Laurentino and Rio do Sul .