Trional Explained

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Iupac Name:2,2-bis(ethylsulfonyl)butane
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Legal Us:Schedule III
Cas Number:76-20-0
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Trional (Methylsulfonal) is a sedative-hypnotic[1] and anesthetic drug with GABAergic actions. It has similar effects to sulfonal, except it is faster acting.[2]

History

Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.[3]

Cultural references

Appeared in Agatha Christie's Murder on the Orient Express, And Then There Were None, and other novels such as John Bude's The Lake District Murder as a sleep-inducing sedative; and in In Search of Lost Time (Sodom and Gomorrah) by Marcel Proust as a hypnotic. Sax Rohmer also references trional in his novel Dope.

See also

Notes and References

  1. Book: 1907 . https://archive.org/stream/cu31924003469677#page/n465/mode/2up/ . Trional . Merck's 1907 Index . New York . Merck & Co. . 448 .
  2. Sajous CE . 1896 . General Therapeutics . Annual of the Universal Medical Sciences . Philadelphia . F. A. Davis . 5 . A-156 .
  3. Book: Drinkwater H . 1924 . Fifty years of medical progress, 1873-1922 . New York . The Macmillan Company . 40 .