| Honorific-Prefix: | The Honorable |
| Trinidad Roxas | |
| Order: | First Lady of the Philippines |
| Term Label: | In role |
| Term Start: | May 28, 1946 |
| Term End: | April 18, 1948 |
| President: | Manuel Roxas |
| Predecessor: | Esperanza Osmeña |
| Successor: | Victoria Quirino-Gonzalez |
| Birth Name: | Trinidad de Leon y Roura |
| Birth Date: | October 4, 1900[1] |
| Birth Place: | San Miguel, Bulacan, Philippine Islands |
| Death Place: | Philippines |
| Restingplace: | Manila North Cemetery |
| Children: | Gerardo Roxas Ruby Roxas |
Trinidad de Leon-Roxas (née de Leon y Roura; October 4, 1900 – June 20, 1995[2]) was the wife of Philippine President Manuel Roxas and the fifth First Lady of the Philippines. They were married in 1921 and had two children, Ruby and Gerardo (Gerry).
A native of San Miguel, Bulacan,[3] De León-Roxas was the daughter of Ceferino de Leon, who was a member of the Malolos Congress. She was also a beauty pageant contestant, having been crowned Carnival Queen (Queen of the Orient) at the Manila Carnival in 1920.[4]
As the country's first lady during the post-war years, De León-Roxas got involved in various charitable organizations such as the White Cross and the Girl Scouts of the Philippines and restored the annual Malacañang Christmas gift-giving begun prior to World War II. The annual gift-giving has become a tradition to this day.
De León-Roxas died on June 20, 1995.