Tricarbonylchloroglycinatoruthenium(II) explained

Tricarbonylchloroglycinatoruthenium(II) is an organoruthenium complex with the formula RuCl(H₂NCH₂CO₂)(CO)₃. A yellow solid, it is an amino acid complex consisting of an octahedral complex with three carbonyls, chloride, and bidentate glycinate ligands. The CO ligands are arranged in a facial geometry. The complex is prepared by treating dichlororuthenium tricarbonyl dimer with sodium glycinate.^[1] The complex has attracted attention as a CO-releasing molecule ("CORM").^{[2] [3]}

References

1. 10.1161/01.RES.0000084381.86567.08. Cardioprotective Actions by a Water-Soluble Carbon Monoxide–Releasing Molecule . 2003 . Clark . James E. . Naughton . Patrick . Shurey . Sandra . Green . Colin J. . Johnson . Tony R. . Mann . Brian E. . Foresti . Roberta . Motterlini . Roberto . Circulation Research . 93 . 2 . e2-8 . 12842916 . 784328 .
2. 10.1021/ja108820s. CORM-3 Reactivity toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl−Lysozyme Complex . 2011 . Santos-Silva . Teresa . Mukhopadhyay . Abhik . Seixas . João D. . Bernardes . Gonçalo J. L. . Romão . Carlos C. . Romão . Maria J. . Journal of the American Chemical Society . 133 . 5 . 1192–1195 . 21204537 .
3. 10.1016/0022-328X(96)06166-9. Metal complexes of biologically important ligands, LXXXVII α-amino carboxylate complexes of palladium(II), iridium(III) and ruthenium(II) from chloro-bridged ortho-metallated metal compounds and [(OC)3Ru(Cl)(μ-Cl)]2 . 1996 . Urban . Reinhold . Krämer . Roland . Mihan . Shahram . Polborn . Kurt . Wagner . Barbara . Beck . Wolfgang . Journal of Organometallic Chemistry . 517 . 1–2 . 191–200 .