Trepipam Explained

Trepipam (INN) is a dopamine receptor agonist of the benzazepine group that was never marketed.[1] It acts specifically as an agonist of the dopamine D1 receptor.[2] It is closed related structurally to fenoldopam, a peripherally acting selective D1 receptor partial agonist which is used as an antihypertensive agent.

Notes and References

  1. Book: Lednicer D . Strategies for Organic Drug Synthesis and Design. 4 March 2009. John Wiley & Sons. 978-0-470-39959-0. 495–.
  2. Goode-Romero G, Winnberg U, Domínguez L, Ibarra IA, Vargas R, Winnberg E, Martínez A . New information of dopaminergic agents based on quantum chemistry calculations . Sci Rep . 10 . 1 . 21581 . December 2020 . 33299000 . 7725812 . 10.1038/s41598-020-78446-4 . 2020NatSR..1021581G .

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