Trametenolic acid explained

Trametenolic acid is an anti-inflammatory sterol isolated from Inonotus obliquus.^[1] Duan et al reported that Trametenolic Acid had exhibited protective effect on the kidneys and ameliorated the progression of Diabetic Nephropathy in db/db Mice (The db/db mice are perfect animal models of type 2 diabetes.) via Nrf2/HO-1 and NF-κB-Mediated Pathways^[2] Trametenolic Acid Mitigated Oxidative Stress in animal studies

Notes and References

1. 23561137. 2013. Ma. L. Chen. H. Dong. P. Lu. X. Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus. 139. 1–4. 503–8. 10.1016/j.foodchem.2013.01.030. Food Chemistry.
2. Duan Q, Tian L, Feng J, Ping X, Li L, Yaigoub H, Li R, Li Y. Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways. J Immunol Res. 2022 Aug 30;2022:6151847. doi: 10.1155/2022/6151847. PMID: 36081452; PMCID: PMC9448586}}