Trafermin Explained
Trafermin (brand name Fiblast), also known as recombinant human basic fibroblast growth factor (rhbFGF), is a recombinant form of human basic fibroblast growth factor (bFGF) which is marketed in Japan as a topical spray for the treatment of skin ulcers.[1] [2] [3] It is also currently in preregistration for the treatment of periodontitis.[4] As a recombinant form of bFGF, trafermin is a potent agonist of the FGFR1, FGFR2, FGFR3, and FGFR4.[5] [6] The drug has been marketed in Japan since June 2001.
External links
Notes and References
- Web site: Trafermin - Kaken Pharmaceutical . AdisInsight . Springer Nature Switzerland AG .
- Web site: Trafermin . Drugs.com .
- Book: Han SK . Growth Factor Therapy . Innovations and Advances in Wound Healing. https://books.google.com/books?id=IY-QCgAAQBAJ&pg=PA206 . 15 September 2015. Springer. 978-3-662-46587-5. 206–.
- Kitamura M, Akamatsu M, Kawanami M, Furuichi Y, Fujii T, Mori M, Kunimatsu K, Shimauchi H, Ogata Y, Yamamoto M, Nakagawa T, Sato S, Ito K, Ogasawara T, Izumi Y, Gomi K, Yamazaki K, Yoshie H, Fukuda M, Noguchi T, Takashiba S, Kurihara H, Nagata T, Hamachi T, Maeda K, Yokota M, Sakagami R, Hara Y, Noguchi K, Furuuchi T, Sasano T, Imai E, Ohmae M, Koizumi H, Watanuki M, Murakami S . 6 . Randomized Placebo-Controlled and Controlled Non-Inferiority Phase III Trials Comparing Trafermin, a Recombinant Human Fibroblast Growth Factor 2, and Enamel Matrix Derivative in Periodontal Regeneration in Intrabony Defects . Journal of Bone and Mineral Research . 31 . 4 . 806–814 . April 2016 . 26547659 . 10.1002/jbmr.2738 . free .
- Book: Barnard JA, McHugh KM . Growth Factors in the Gastrointestinal Tract . Barrett KE, Ghishan FK, Merchant JL, Said HM, Wood JD . Physiology of the Gastrointestinal Tract . https://books.google.com/books?id=CNwLlih2C60C&pg=PA216 . 10 May 2006 . Academic Press . 978-0-08-045615-7 . 216–.
- Book: Hamid M. Said. Physiology of the Gastrointestinal Tract, Two Volume Set. 4 July 2012. Academic Press. 978-0-12-382027-3. 235–.
