Toby Gibson Explained

Toby Gibson
Birth Name:Toby James Gibson
Fields:Computational biology
Bioinformatics
Short linear motifs
Protein interactions
Sequence alignment
Workplaces:Laboratory of Molecular Biology
European Molecular Biology Laboratory
Alma Mater:University of Edinburgh (BSc)
University of Cambridge (PhD)
Thesis Title:Studies on the Epstein-Barr virus genome
Thesis Url:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.352786
Thesis Year:1984
Doctoral Advisors:)-->
Known For:Clustal[1]

Toby James Gibson is a group leader and biochemist at the European Molecular Biology Laboratory (EMBL) in Heidelberg known for his work on Clustal.[1] [2] According to Nature, Gibson's co-authored papers describing Clustal[2] [3] are among the top ten most highly cited scientific papers of all time.[4]

Education

Gibson was educated at the University of Edinburgh[5] and went on to his PhD at the University of Cambridge in 1984 on the genome of the Epstein–Barr virus[6] while working in the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB).[5]

Career and research

Gibson was a postdoctoral research fellow with Sydney Brenner before moving to EMBL in 1986.[5] He was appointed a staff scientist in 1991 and a team leader in 1996 where he has worked since.

Gibson’s research interests are in computational biology, bioinformatics, short linear motifs, protein–protein interactions and biological sequence alignment. His laboratory developed and hosts the Eukaryotic Linear Motif (ELM) resource.[7]

Notes and References

  1. Thompson. Julie D.. Higgins. Desmond G.. Desmond G. Higgins. Gibson. Toby J.. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Research. 22. 22. 1994. 4673–4680. 0305-1048. 10.1093/nar/22.22.4673. 7984417 . 308517 .
  2. Thompson. J.. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Research. 25. 24. 1997. 4876–4882. 1362-4962. 10.1093/nar/25.24.4876. 9396791 . 147148 .
  3. Thompson . J. D. . Higgins . D. G. . Gibson . T. J. . Toby Gibson. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice . Nucleic Acids Research . 22 . 22 . 4673–4680 . 1994 . 7984417 . 308517 . 10.1093/nar/22.22.4673.
  4. 10.1038/514550a. 25355343. The top 100 papers: Nature explores the most-cited research of all time. Nature. 514. 7524. 550–3. 2014. Van Noorden . R. . Maher . B. . Nuzzo . R.. Regina Nuzzo . free.
  5. Web site: https://web.archive.org/web/20190705185224/https://rtg2467.uni-halle.de/scientific-advisory-board/toby-james-gibson/. Anon. 2019. 2019-07-05. Toby (James) Gibson: EMBL, Heidelberg, Germany. uni-halle.de. Martin Luther University of Halle-Wittenberg.
  6. PhD. University of Cambridge. Studies on the Epstein-Barr virus genome. Toby James. Gibson. 1984. . cam.ac.uk. 499859334.
  7. Kumar. Manjeet. Gouw. Marc. Michael. Sushama. Sámano-Sánchez. Hugo. Pancsa. Rita. Glavina. Juliana. Diakogianni. Athina. Valverde. Jesús Alvarado. Bukirova. Dayana. Čalyševa. Jelena. Palopoli. Nicolas. Davey. Norman E. Chemes. Lucía B. Gibson. Toby J. ELM—the eukaryotic linear motif resource in 2020. Nucleic Acids Research. 2019. 0305-1048. 10.1093/nar/gkz1030. 31680160. free. 7145657.