Tobias Huber Explained

Tobias Huber (25 August 1971 in Waldkirch) is a German nephrologist and internist. He is university professor and Director and Chairman of the III. Department of Medicine[1] at the University Medical Center Hamburg-Eppendorf.[2] [3] [4]

Biography

Huber studied human medicine in Freiburg, Vienna and Tampa from 1992 until 1999.[5] [6] [7] Following his promotion at the Institute of Physiology in Freiburg, he was medical assistant at the nephrologists unit of the University Hospital Freiburg. From 2003 until 2006 Huber was receiving an Emmy Noether scholarship of the Deutsche Forschungsgemeinschaft[8] and worked as Postdoctoral Fellow at the Department of Immunology and Pathology at Washington University in St. Louis.[9] [10] [11] After his habilitation in 2007, Huber was certified as a specialist in internal medicine and became group leader of an Emmy Noether research group in Freiburg.[11] In 2012 Huber had been elected as Heisenberg Fellow and since 2013 he has been holding a Heisenberg professorship for Medicine and Nephrology at the University Medical Center Freiburg.[5] [6] [7] [8] From 2015- 2017 Huber was Vice Chair of the Department of Medicine IV, Chief of the Division of Chronic Kidney Disease at the University Medical Center Freiburg and furthermore, Co-Director of the Center of Systems Biology (ZBSA).[5] [6] [7] [8] [12] Since April 2017 he is the Director and Chairman of the III. Department of Medicine[1] at the University Medical Center Hamburg-Eppendorf.[2] [3] [4] Huber is a Fellow of the American Society of Nephrology (FASN)[13] and a member of the American Society for Clinical Investigation[9] a member of the Association of American Physicians and a member of the German National Academy of Sciences – Leopoldina.

Scientific contribution

Huber's research focus is to understand the complex signaling networks that regulate the development, maintenance and disease progression of the kidney.[14] [15] [16] [17] [9] [10] [11] His team identified several molecular mechanisms important for renal development, maintenance, ageing and disease of the kidney.[16] [18] [19] [9] [20] More recently his team made novel discoveries regarding the tropism and organ injury caused by SARS-CoV-2 (Puelles et al. NEJM 2020, Braun et al., LANCET 2020, Gross et al., LANCET, 2020).

External links

Notes and References

  1. Web site: UKE - Arztprofil - Tobias B. Huber. www.uke.de.
  2. Web site: UKE - Pressemitteilung - Nierenspezialist aus Freiburg übernimmt Leitung der III. Medizinischen Klinik des UKE. www.uke.de.
  3. Web site: Aufgaben und Ämter. Deutscher Ärzteverlag GmbH, Redaktion Deutsches. Ärzteblatt. 12 May 2017. aerzteblatt.de.
  4. Web site: Nierenspezialist aus Freiburg übernimmt Leitung der III. Medizinischen Klinik des UKE. hamburg.de.
  5. Web site: Prof. Dr. Tobias B. Huber — Freiburg Institute for Advanced Studies – FRIAS. www.frias.uni-freiburg.de.
  6. Web site: CV Tobias Huber. Huberlab Freiburg.
  7. Web site: Tobias B. Huber - Nephrolab.org. www.nephrolab.org.
  8. Web site: DFG - GEPRIS - Professor Dr. Tobias B. Huber. gepris.dfg.de.
  9. Web site: The American Society for Clinical Investigation. www.the-asci.org.
  10. Web site: Young Investigator Attains Recognition for Podocyte Research - Kidney News. www.kidneynews.org.
  11. Web site: Prof. Dr. Tobias B. Huber — Freiburg Institute for Advanced Studies – FRIAS. www.frias.uni-freiburg.de.
  12. Web site: Tobias B. Huber MD. Huberlab Freiburg. dead. https://web.archive.org/web/20160531023451/http://www.tbhuber.org/team/pi-tobias-b-huber-md. 2016-05-31.
  13. Web site: FASN. asn-online.org/membership/fasn/inductees.aspx.
  14. Huber, T. B., Schermer, B., Muller, R. U., Hohne, M., Bartram, M., Calixto, A., Hagmann, H., Reinhardt, C., Koos, F., Kunzelmann, K., Shirokova, E., Krautwurst, D., Harteneck, C., Simons, M., Pavenstadt, H., Kerjaschki, D., Thiele, C., Walz, G., Chalfie, M., and Benzing, T. 2006. Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A 103:17079-86. .
  15. Huber, T. B., Kwoh, C., Wu, H., Asanuma, K., Godel, M., Hartleben, B., Blumer, K. J., Miner, J. H., Mundel, P., and Shaw, A. S. 2006. Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest 116:1337-45. .
  16. Grahammer, F., Schell, C., and Huber, T. B. 2013. The podocyte slit diaphragm--from a thin grey line to a complex signalling hub. Nat Rev Nephrol 9:587-98. .
  17. Grahammer, F., Nesterov, V., Ahmed, A., Steinhardt, F., Sandner, L., Arnold, F., Cordts, T., Negrea, S., Bertog, M., Ruegg, M. A., Hall, M. N., Walz, G., Korbmacher, C., Artunc, F., and Huber, T. B. 2016. mTORC2 critically regulates renal potassium handling. J Clin Invest .
  18. Hartleben, B., Godel, M., Meyer-Schwesinger, C., Liu, S., Ulrich, T., Kobler, S., Wiech, T., Grahammer, F., Arnold, S. J., Lindenmeyer, M. T., Cohen, C. D., Pavenstadt, H., Kerjaschki, D., Mizushima, N., Shaw, A. S., Walz, G., and Huber, T. B. 2010. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 120:1084-96. .
  19. Godel, M., Hartleben, B., Herbach, N., Liu, S., Zschiedrich, S., Lu, S., Debreczeni-Mor, A., Lindenmeyer, M. T., Rastaldi, M. P., Hartleben, G., Wiech, T., Fornoni, A., Nelson, R. G., Kretzler, M., Wanke, R., Pavenstadt, H., Kerjaschki, D., Cohen, C. D., Hall, M. N., Ruegg, M. A., Inoki, K., Walz, G., and Huber, T. B. 2011. Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. In Invest 121:2197-209. .
  20. Web site: BIOSS Member Wins Young Investigator Award 2012. 6 December 2012. www.bioss.uni-freiburg.de.

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