Tildipirosin Explained

Tradename:Zuprevo
Dailymedid:Tildipirosin
Routes Of Administration:Intramuscular, subcutaneous
Atcvet:Yes
Atc Prefix:J01
Atc Suffix:FA96
Legal Ca:Rx-only
Legal Us:Rx-only
Legal Us Comment:[1] [2]
Legal Eu:Rx-only
Cas Number:328898-40-4
Pubchem:24860548
Drugbank:DB11470
Chemspiderid:30790722
Unii:S795AT66JB
Chembl:3039509
C:41
H:71
N:3
O:8
Smiles:CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O)N(C)C)O)CCN3CCCCC3)C)\C)CN4CCCCC4
Stdinchi:1S/C41H71N3O8/c1-8-35-32(26-44-20-13-10-14-21-44)23-27(2)15-16-33(45)28(3)24-31(17-22-43-18-11-9-12-19-43)40(29(4)34(46)25-36(47)51-35)52-41-39(49)37(42(6)7)38(48)30(5)50-41/h15-16,23,28-32,34-35,37-41,46,48-49H,8-14,17-22,24-26H2,1-7H3/b16-15+,27-23+/t28-,29+,30-,31+,32-,34-,35-,37+,38-,39-,40-,41+/m1/s1
Stdinchikey:HNDXPZPJZGTJLJ-UEJFNEDBSA-N

Tildipirosin, sold under the brand name Zuprevo is an antibiotic used in pigs and cattle.

Medical uses

In the United States, tildipirosin is indicated for the treatment or control of bovine respiratory disease associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in beef and non-lactating dairy cattle.

In the European Union, tildipirosin is indicated for the treatment and metaphylaxis of swine respiratory disease associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, and Haemophilus parasuis sensitive to tildipirosin;[3] and for the treatment and prevention of bovine respiratory disease associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni sensitive to tildipirosin.

Notes and References

  1. Web site: Zuprevo- tildipirosin injection, solution . DailyMed . U.S. National Library of Medicine . 11 January 2013 . 21 August 2023.
  2. Book: Budde JA, McCluskey DM . Plumb's Veterinary Drug Handbook . 2023 . Wiley . 978-1-394-17220-7 . 1235 . Tenth.
  3. Web site: Zuprevo EPAR . European Medicines Agency . 3 February 2022 . 21 August 2023. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.