Thymolphthalein Explained

Thymolphthalein is a phthalein dye used as an acidbase (pH) indicator. Its transition range is around pH 9.3–10.5. Below this pH, it is colorless; above, it is blue. The molar extinction coefficient for the blue thymolphthalein dianion is 38,000 M−1 cm−1 at 595 nm.[1]

Thymolphthalein is also known to have use as a laxative[2] and for disappearing ink.[3]

Preparation

Thymolphthalein can be synthesized from thymol and phthalic anhydride.

See also

Notes and References

  1. Hahn HH . Cheuk SF . Elfenbein S . Wood WB . Studies on the Pathogenesis of Fever: Xix. Localization of Pyrogen in Granulocytes. The Journal of Experimental Medicine. 131 . 4 . 701–9 . April 1970 . 5430784 . 2138774 . 10.1084/jem.131.4.701.
  2. Hubacher . MH . Doernberg . S . Horner . A . 1953 . Laxatives: chemical structure and potency of phthaleins and hydroxyanthraquinones . Journal of the American Pharmaceutical Association . 42 . 1. 23–30 . 13034620 . 10.1002/jps.3030420108 .
  3. Web site: Disappearing Ink. Katz. David A.. 1982. www.chymist.com. August 14, 2017.