Thunberginol A Explained

Thunberginol A is an isocoumarin found in Hydrangea macrophylla[1] and the herbal preparation hydrangeae dulcis folium which is produced from its leaves.[2] [3]

Notes and References

  1. Matsuda . H. . Shimoda . H. . Yamahara . J. . Yoshikawa . M. . Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols a and F from Hydrangea macrophylla SERINGE var. Thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats . Biological & Pharmaceutical Bulletin . 22 . 8 . 870–872 . 1999 . 10480329. . 10.1248/bpb.22.870. free .
  2. Yamahara . J. . Matsuda . H. . Shimoda . H. . Wariishi . N. . Yagi . N. . Murakami . N. . Yoshikawa . M. . Effects of thunberginol a contained in Hydrangeae dulcis forium on types I-IV allergies . Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica . 105 . 5 . 365–379 . 1995 . 10.1254/fpj.105.365 . 7628785. ja. free .
  3. Matsuda . H. . Shimoda . H. . Yamahara . J. . Yoshikawa . M. . Immunomodulatory activity of thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens . 10.1016/S0960-894X(97)10221-9 . Bioorganic & Medicinal Chemistry Letters . 8 . 3 . 215–20 . 1998 . 9871657.

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