| Official Name: | Thong Saen Khan |
| Native Name: | ทองแสนขัน |
| Native Name Lang: | th |
| Settlement Type: | District |
| Subdivision Type: | Country |
| Subdivision Name: | Thailand |
| Subdivision Type1: | Province |
| Subdivision Name1: | Uttaradit |
| Subdivision Type2: | Seat |
| Subdivision Name2: | Bo Thong |
| Subdivision Type3: | Tambon |
| Subdivision Type4: | Muban |
| Established Title: | District established |
| Population Total: | 33042 |
| Population As Of: | 2005 |
| Blank Name Sec1: | Postal code |
| Blank Info Sec1: | 53230 |
| Blank Name Sec2: | Geocode |
| Blank Info Sec2: | 5309 |
| Timezone: | ICT |
| Utc Offset: | +7 |
| Coordinates: | 17.4753°N 100.3336°W |
Thong Saen Khan (Thai: ทองแสนขัน, in Thai pronounced as /tʰɔ̄ːŋ sɛ̌ːn kʰǎn/) is a district (amphoe) in the southern part of Uttaradit province, northern Thailand.
Neighboring districts are (from the southwest clockwise) Phichai, Tron, Mueang Uttaradit, Tha Pla, Nam Pat of Uttaradit Province, Chat Trakan and Wat Bot of Phitsanulok province
The minor district (king amphoe) was created on 1 July 1983, when four tambon were split off from Tron district.[1] It was upgraded to a full district on 21 May 1990.[2]
The district is divided into four sub-districts (tambons), which are further subdivided into 45 villages (mubans). The township (thesaban tambon) Thong Saen Khan covers parts of tambon Bo Thong. There are a further four tambon administrative organizations (TAO).
| No. | Name | Thai name | Villages | Pop. | ||
|---|---|---|---|---|---|---|
| 1. | Phak Khuang | ผักขวง | 14 | 9,198 | ||
| 2. | Bo Thong | บ่อทอง | 14 | 12,287 | ||
| 3. | Pa Khai | ป่าคาย | 9 | 6,030 | ||
| 4. | Nam Phi | น้ำพี้ | 8 | 5,527 |