| Honorific-Prefix: | Most Reverend |
| Thomas Vásquez de Liaño | |
| Bishop Elect of Paraguay | |
| Church: | Catholic Church |
| Diocese: | Diocese of Paraguay |
| Term: | 1596–1599 |
| Predecessor: | Alfonso Guerra (bishop) |
| Successor: | Martín Ignacio de Loyola |
| Birth Date: | 1546 |
| Death Date: | 28 December 1599 (age 53) |
| Death Place: | Asuncion, Paraguay |
Thomas Vásquez de Liaño (1546 – 28 December 1599) was a Roman Catholic prelate who served as Bishop of Paraguay (1596–1599).[1]
On 18 December 1596, Thomas Vásquez de Liaño was appointed during the papacy of Pope Clement VIII as Bishop of Paraguay.[2] He died before he was consecrated bishop on 28 December 1599.