| Thomas Rothmaler Mitchell | |
| Birth Date: | May 1783 |
| Birth Place: | Georgetown, South Carolina |
| Death Place: | Georgetown, South Carolina |
| State1: | South Carolina |
| District1: | 3rd |
| Term Start3: | March 4, 1821 |
| Term End3: | March 3, 1823 |
| Predecessor3: | James Ervin |
| Successor3: | Robert B. Campbell |
| Term Start2: | March 4, 1825 |
| Term End2: | March 3, 1829 |
| Predecessor2: | Robert B. Campbell |
| Successor2: | John Campbell |
| Term Start1: | March 4, 1831 |
| Term End1: | March 3, 1833 |
| Predecessor1: | John Campbell |
| Successor1: | Thomas Singleton |
| Office4: | Member of the South Carolina House of Representatives from Georgetown District |
| Term Start4: | November 28, 1814 |
| Term End4: | December 18, 1819 |
| Office5: | Member of the South Carolina House of Representatives from Horry District |
| Term5: | November 29, 1809 - December 19, 1809 |
| Party: | Democratic-Republican |
| Otherparty: | Jacksonian |
| Profession: | lawyer, politician |
| Alma Mater: | Harvard University |
Thomas Rothmaler Mitchell (May 1783November 2, 1837) was an early-19th-century American lawyer and politician who served as a U.S. Representative from South Carolina.
Born in Georgetown, South Carolina, in May 1783, Mitchell graduated from Harvard University in 1802, where he studied law. He was admitted to the bar in 1808, and commenced practice in Georgetown, South Carolina.
He served as member of the state house of representatives in 1809 and from 1814 to 1819.
Mitchell was elected as a Democratic-Republican to the Seventeenth Congress (March 4, 1821 – March 3, 1823). He was an unsuccessful candidate for reelection in 1822 to the Eighteenth Congress. He was then elected as a Jacksonian to the Nineteenth and Twentieth Congresses (March 4, 1825 – March 3, 1829). He was an unsuccessful candidate for reelection in 1828 to the Twenty-first Congress.
He was reelected as a Jacksonian to the Twenty-second Congress (March 4, 1831– March 3, 1833). He was an unsuccessful candidate for reelection in 1832 to the Twenty-third Congress.
He died in Georgetown, South Carolina, November 2, 1837.