| Thomas Henley | |
| State: | Indiana |
| Term Start: | March 4, 1843 |
| Term End: | March 3, 1849 |
| Predecessor: | Charles M. La Follette |
| Successor: | Winfield K. Denton |
| Office1: | 27th Speaker of the Indiana House of Representatives |
| Term Start1: | December 5, 1842 |
| Term End1: | December 4, 1843 |
| Predecessor1: | John W. Davis |
| Successor1: | Andrew L. Robinson |
| State House2: | Indiana |
| District2: | Clark County |
| Term Start2: | December 5, 1832 |
| Term End2: | December 4, 1843 |
| Birth Date: | 18 June 1808 |
| Birth Place: | Richmond, Indiana, U.S. |
| Death Place: | Mendocino County, California, U.S |
| Education: | Indiana University |
Thomas Jefferson Henley (June 18, 1808 – May 1, 1875) was a U.S. Representative from Indiana, father of Barclay Henley.
Born in Richmond, Indiana, Henley attended Indiana University at Bloomington. He studied law and was admitted to the bar in 1828 and commenced practice in Richmond, Indiana. He also engaged in banking. He served as member of the State house of representatives between 1832-1842 and served as speaker in 1840.
Henley was elected as a Democrat to the Twenty-eighth, Twenty-ninth, and Thirtieth Congresses (March 4, 1843 – March 3, 1849). He served as chairman of the Committee on Patents (Twenty-eighth and Twenty-ninth Congresses). He moved to California in 1849 and engaged in banking in Sacramento. He served as member of the first State house of representatives between 1851-1853. He then served as Superintendent of Indian Affairs of California between 1855–1858, during which time he oversaw and instigated the Round Valley Settler Massacres of 1856–1859. His last job was as the postmaster of San Francisco between 1860-1864.
Henley died in Mendocino County, California. He was interred in Santa Rosa Cemetery, Santa Rosa, California.