| Thomas Jefferson Strait | |
| Image Name: | File:Thomas_Jefferson_Strait.jpg |
| Birth Date: | 25 December 1846 |
| Birth Place: | Chester District, South Carolina |
| Death Place: | Lancaster, South Carolina |
| State: | South Carolina |
| District: | 5th |
| Term Start: | March 4, 1893 |
| Term End: | March 3, 1899 |
| Predecessor: | John J. Hemphill |
| Successor: | David E. Finley |
| Office2: | Member of the South Carolina Senate |
| Term2: | 1890 - 1893 |
| Party: | Democrat |
| Spouse: | Katherine Lathrop |
| Alma Mater: | South Carolina Medical College |
| Occupation: | physician |
| Rank: | Sergeant |
| Unit: | 6th South Carolina Infantry, 24th South Carolina Infantry |
| Serviceyears: | 1862 - 1865 |
| Battles: | American Civil War |
Thomas Jefferson Strait (December 25, 1846 – April 18, 1924) was a U.S. Representative from South Carolina.
Born in Chester District, South Carolina, Strait attended the common schools of Mayesville, South Carolina, and Cooper Institute, Mississippi.During the Civil War entered the Confederate States Army in 1862 and served throughout the war, first in Company A, Sixth Regiment of Infantry, and later as sergeant in Company H, Twenty-fourth Regiment, Gist's brigade.He engaged in agricultural pursuits.He taught school in Ebenezer, South Carolina, in 1880.He was graduated from South Carolina Medical College at Charleston in 1885 and practiced medicine.He served as member of the State senate 1890-1893.
Strait was elected as a Democrat to the Fifty-third, Fifty-fourth, and Fifty-fifth Congresses (March 4, 1893 – March 3, 1899).He was an unsuccessful candidate for renomination in 1898 to the Fifty-sixth Congress.He resumed the practice of his profession in Lancaster, South Carolina, and died there on April 18, 1924.He was interred in Westside Cemetery.