| Thomas Cholmondeley | |
| Term Start1: | 1670 |
| Term End1: | 1679 |
| Term Start2: | 1685 |
| Term End2: | 1687 |
| Birth Date: | 15 September 1627 |
| Death Place: | Vale Royal, Cheshire |
| Resting Place: | Church Minshull, Cheshire |
| Children: | with Jane: with Anne: |
Thomas Cholmondeley (15 September 1627 – 26 February 1702), of Vale Royal, Cheshire was an English landowner and politician who sat in the House of Commons between 1670 and 1687. He was elected MP for Cheshire in 1670 and 1685 and was Sheriff of Cheshire from 1660 to 1661.
Cholmondeley was born on 15 September 1627, the third son of Thomas Cholmondeley (1595 – 1653) of Vale Royal, Cheshire and Elizabeth Minshull, daughter of John Minshull of Minshull and Frances Egerton of Oulton.
He married, firstly, Jane Tollemache (d. 18 April 1666), daughter of Sir Lionel Tollemache, 2nd Baronet of Helmingham Hall in Suffolk and Elizabeth Stanhope, daughter of John Stanhope, 1st Baron Stanhope of Harrington, by whom he had six sons and seven daughters:
He married, secondly, Anne St. John, daughter of Sir Walter St John, 3rd Baronet of Lydiard Tregoze, Wiltshire, by whom he had three sons and a daughter:
He died on 26 February 1702 at Vale Royal and was buried on 2 March at Church Minshull, Cheshire. "Had he not lived in times of difficulties and divisions", wrote his Whig neighbour, "he had been the most popular commoner at home and abroad."