Sir Thomas Chamberlayne, 1st Baronet (died 1643), of Wickham, Oxfordshire supported the Royalist cause in the English Civil War. He was Sheriff of Oxfordshire in 1643
Sir Thomas Chamberlayne, 2nd Baronet (c. 1635–1682), one of few men to receive a renewal of the baronetcy from the Lord Protector Oliver Cromwell