| Cabinet Name: | Third Smuts Cabinet |
| Cabinet Number: | 10th |
| Jurisdiction: | the Union of South Africa (since the 1909 South Africa Act) |
| Flag: | Flag of South Africa (1928–1982).svg |
| Flag Border: | true |
| Incumbent: | 1943–1948 |
| State Head Title: | Monarch |
| State Head: | King George VI |
| Governor General Title: | Governor-General |
| Government Head Title: | Prime Minister |
| Government Head: | Jan Smuts |
| Legislature Status: | Majority |
| Opposition Party: | Reunited National Party |
| Opposition Leader: | Daniël Malan |
| Election: | 1943 election |
| Previous: | Hertzog IV |
| Successor: | Malan I |
| Post | Minister | Term | Party | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Prime Minister | Gen. Jan Smuts | 1939 | 1948 | UP | |||||
| Minister of Defence | |||||||||
| Minister of External Affairs | |||||||||
| Deputy Prime Minister | The Hon. J. F. H. Hofmeyr MP | 1943 | 1948 | align=center | UP | ||||
| Minister of Agriculture and Forestry | The Hon. J. G. N. Strauss MP | 1944 | 1948 | align=center | UP | ||||
| The Hon. W. R. Collins MP | 1938 | 1944 | align=center | UP | |||||
| Minister of Economic Development | The Hon. Sidney Waterson MP | 1941 | 1948 | align=center | UP | ||||
| Minister of Education | The Hon. J. F. H. Hofmeyr MP | 1939 | 1948 | align=center | UP | ||||
| Minister of Finance | The Hon. J. F. H. Hofmeyr MP | 1939 | 1948 | align=center | UP | ||||
| Minister of Interior Affairs |
| 1943 | 1948 | align=center | UP | ||||
| Minister of Justice | The Hon. Harry Lawrence MP | 1945 | 1948 | align=center | UP | ||||
| The Hon. C. F. Steyn MP | 1939 | 1945 | align=center | UP | |||||
| Minister of Labour | The Hon. C. F. Steyn MP | 1945 | 1948 | align=center | UP | ||||
| The Hon. Walter Madeley MP | 1939 | 1945 | align=center | ||||||
| Minister of Lands and Irrigation |
| 1939 | 1948 | align=center | UP | ||||
| Minister of Mines | The Hon. C. F. Stallard MP | 1939 | 1945 | align=center | Dominion | ||||
| Minister of Native Affairs |
| 1943 | 1948 | align=center | UP | ||||
| Minister of Posts and Telegraphs |
| 1933 | 1945 | align=center | UP | ||||
| Minister of Public Works |
| 1933 | 1945 | align=center | UP | ||||
| Minister of Transport | The Hon. F. C. Sturrock MP | 1939 | 1948 | align=center | UP | ||||
| Minister of Welfare and Demobilisation | The Hon. Harry Lawrence MP | 1939 | 1948 | align=center | UP | ||||