| Cabinet Name: | Third Vorster Cabinet |
| Cabinet Number: | 5th |
| Jurisdiction: | the Republic of South Africa (since the 1961 Constitution) |
| Flag: | Flag of South Africa (1928–1982).svg |
| Flag Border: | true |
| Incumbent: | 1974–1978 |
| State Head Title: | State President |
| Government Head Title: | Prime Minister |
| Political Party: | National Party |
| Legislature Status: | Majority |
| Previous: | Vorster II |
| Successor: | Botha I |
| Prime Minister | Johannes Vorster | 29 April 1974 | 10 October 1978 | |
| Foreign Affairs | Hilgard Muller Pik Botha | 29 April 1974 May 1977 | May 1977 10 October 1978 | |
| Defense | Pieter Willem Botha | 29 April 1974 | 10 October 1978 | |
| Finance | Nicolaas Diederichs Owen Horwood | 29 April 1974 February 1975 | February 1975 10 October 1978 | |
| Home Affairs | Connie Mulder Alwyn Schlebusch | 29 April 1974 August 1978 | August 1978 10 October 1978 | |
| Information | Connie Mulder | 29 April 1974 | August 1978 | |
| Justice, Police and Prisons | Jimmy Kruger | 29 April 1974 | 10 October 1978 | |
| Transport | Lourens Muller | 29 April 1974 | 10 October 1978 | |
| Labour | Marais Viljoen Stephanus Petrus Botha | 29 April 1974 22 January 1976 | 22 January 1976 10 October 1978 | |
| Mining | Piet Koornhof Stephanus Petrus Botha | 29 April 1974 22 January 1976 | 22 January 1976 10 October 1978 | |
| Immigration | Piet Koornhof Alwyn Schlebusch | 29 April 1974 22 January 1976 | 22 January 1976 10 October 1978 | |
| Sport and Recreation | Piet Koornhof | 29 April 1974 | 10 October 1978 | |
| Economic Affairs | Owen Horwood Chris Heunis | 29 April 1974 February 1975 | February 1975 10 October 1978 | |
| Bantu Administration, Education and Development from January 1978: Bantu Education and Development | Michiel Coenraad Botha Willem Cruywagen | 29 April 1974 January 1978 | January 1978 10 October 1978 | |
| Plural Development | Connie Mulder | January 1978 | 10 October 1978 | |
| National Education | Johannes van der Spuy Piet Koornhof Willem Cruywagen | 29 April 1974 22 January 1976 January 1978 | 22 January 1976 January 1978 10 October 1978 | |
| Public Works | Abraham du Plessis Alwyn Schlebusch | 29 April 1974 1976 | 1975 10 October 1978 | |
| Agriculture | Hendrik Schoeman | 29 April 1974 | 10 October 1978 | |
| Environment, Water Affairs and Forestry | Stephanus Petrus Botha Abraham Raubenheimer | 29 April 1974 1976 | 1976 10 October 1978 | |
| Social Welfare and Pensions | Johannes van der Spuy Frederik Willem de Klerk | 29 April 1974 January 1978 | January 1978 10 October 1978 | |
| Post, Telegraphs and Telecommunication | Marais Viljoen Johannes van der Spuy Frederik Willem de Klerk | 29 April 1974 22 January 1976 January 1978 | 22 January 1976 January 1978 10 October 1978 | |
| Health | Schalk van der Merwe | 29 April 1974 | 10 October 1978 | |
| Planning and Statistics | Jannie Loots Schalk van der Merwe | 29 April 1974 23 January 1976 | 23 January 1976 10 October 1978 | |
| Tourism and Indian Population Affairs | Chris Heunis Marais Steyn | 29 April 1974 February 1975 | February 1975 10 October 1978 | |
| Community Development | Abraham du Plessis Marais Steyn | 29 April 1974 February 1975 | February 1975 10 October 1978 | |
| Coloured Affairs, Rehoboth Homeland and Nama 1976: Coloured Affairs | Schalk van der Merwe Hennie Smit | 29 April 1974 1976 | 1976 10 October 1978 |