| Journal of Clinical Investigation | |
| Cover: | Journal_of_Clinical_Investigation_sample_cover_image_(August_2015).jpg |
| Editor: | Elizabeth M. McNally |
| Discipline: | Biomedicine |
| Abbreviation: | J. Clin. Investig. |
| Nlm: | J Clin Invest |
| Publisher: | American Society for Clinical Investigation |
| Country: | United States |
| Frequency: | Semi-monthly |
| History: | 1924-present |
| Openaccess: | Hybrid |
| Impact: | 13.3 |
| Impact-Year: | 2023 |
| Website: | http://www.jci.org/ |
| Link1: | https://www.jci.org/current |
| Link1-Name: | Online access |
| Link2: | http://www.jci.org/archive |
| Link2-Name: | Online archive |
| Oclc: | 01445593 |
| Lccn: | 27010044 |
| Coden: | JCINAO |
| Issn: | 0021-9738 |
| Eissn: | 1558-8238 |
The Journal of Clinical Investigation is a semi-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation. Articles focus on the mechanisms of disease, with an emphasis on basic research, early-stage clinical studies in humans, and new research tools and techniques. The journal also publishes reviews in edited series or as stand-alone articles, commentaries on research, editorials, and feature items. The editor-in-chief is Elizabeth M. McNally (Northwestern University).
The journal is abstracted and indexed in:According to the Journal Citation Reports, the journal has a 2023 impact factor of 13.3.[1]
The following persons are or have been editor-in-chief of the journal:
, the following articles have received the most citations according to Scopus: