| The Best of Mac Dre II | |
| Type: | greatest |
| Artist: | Mac Dre |
| Cover: | The Best of Mac Dre II.jpg |
| Released: | November 23, 2004 |
| Genre: | West Coast hip hop, G-funk, hyphy, gangsta rap |
| Label: | Thizz Entertainment |
| Prev Title: | The Best of Mac Dre |
| Prev Year: | 1993 |
| Next Title: | The Best of Mac Dre Vol. 3 |
| Next Year: | 2006 |
The Best of Mac Dre 2 is a 2004 two-disc compilation album by hyphy San Francisco Bay Area rapper Mac Dre.