| Thankgod Amaefule | |
| Birth Date: | 16 December 1984 |
| Birth Place: | Port Harcourt, Nigeria |
| Height: | 1.860NaN0 |
| Position: | Striker |
| Youthyears1: | 1994–1999 |
| Youthclubs1: | Veria |
| Years1: | 2000 |
| Years2: | 2000–2003 |
| Years3: | 2003–2005 |
| Years4: | 2005–2007 |
| Years5: | 2007–2008 |
| Years6: | 2009–2012 |
| Years7: | 2012–2017 |
| Clubs6: | Sharks |
| Clubs7: | Heartland |
| Caps3: | 8 |
| Caps4: | 35 |
| Goals3: | 0 |
| Goals4: | 8 |
| Nationalyears1: | 2010 |
| Nationalteam1: | Nigeria |
| Nationalcaps1: | 1 |
| Nationalgoals1: | 0 |
Thankgod Amaefule (born 16 December 1984 in Port Harcourt) is a Nigerian former professional footballer who played as a striker.
Amaefule joined Dolphins in the summer of 2007, after playing several seasons in Poland and Greece, including Veria in the Greek second level. He was excluded from the remainder of Dolphins' 2008 CAF Confederation Cup campaign because of insubordination and inciting disunity. He transferred to crosstown rival Sharks and was a part of their run to the FA Cup final. He played his only match for Nigeria on 3 March 2010 against DR Congo.
His brother is Napoleon Amaefule.