| Tezozomoctzin | |
| Spouse: | Atotoztli II |
| Issue: | Axayacatl, Tizoc, Ahuitzotl |
| Father: | Itzcoatl |
Tezozomoctzin (Tezozomoc pronounced as /nci/) was a son of Itzcoatl, the fourth Aztec ruler (tlatoani) of Tenochtitlan.
Tezozomoctzin never became ruler himself, but he was married to Atotoztli II, daughter his cousin of Moctezuma I (the fifth ruler)
They had three sons that each would become rulers: Axayacatl, Tizoc, and Ahuitzotl — would become the sixth, seventh and eighth rulers, respectively. A fourth son Huitzilihuitl is listed in the genealogy, but was never ruler and has no listed children.
His daughter Chalchiuhnenetzin married Moquihuix, ruler of Tlatelolco altepetl.