Tetrindole Explained

Tetrindole was a drug candidate that functions by reversibly inhibiting monoamine oxidase A; it was first synthesized in Moscow in the early 1990s.[1] Tetrindole is similar in its chemical structure to pirlindole (Pyrazidol), and metralindole.[2]

Notes and References

  1. Medvedev AE, Kirkel AA, Kamyshanskaya NS, Moskvitina TA, Axenova LN, Gorkin VZ, Andreeva NI, Golovina SM, Mashkovsky MD . 6 . Monoamine oxidase inhibition by novel antidepressant tetrindole . Biochemical Pharmacology . 47 . 2 . 303–8 . January 1994 . 8304974 . 10.1016/0006-2952(94)90021-3 .
  2. Ramsay RR, Gravestock MB . Monoamine oxidases: to inhibit or not to inhibit . Mini Reviews in Medicinal Chemistry . 3 . 2 . 129–36 . March 2003 . 12570845 . 10.2174/1389557033405287 .

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