Tertatolol Explained

Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.^[1]

Tertatolol has also been shown to act as a serotonin 5-HT_1A and 5-HT_1B receptor antagonist, similarly to propranolol and pindolol.^{[2] [3] [4]}

See also

• Hydroxytertatolol

Notes and References

1. Book: Swiss Pharmaceutical Society . Index Nominum 2000: International Drug Directory (Book with CD-ROM) . Medpharm Scientific Publishers . Boca Raton . 2000 . 3-88763-075-0 .
2. Langlois M, Brémont B, Rousselle D, Gaudy F . Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors . European Journal of Pharmacology . 244 . 1 . 77–87 . January 1993 . 8093601 . 10.1016/0922-4106(93)90061-d .
3. Jolas T, Haj-Dahmane S, Lanfumey L, Fattaccini CM, Kidd EJ, Adrien J, Gozlan H, Guardiola-Lemaitre B, Hamon M . 6 . (-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain . Naunyn-Schmiedeberg's Archives of Pharmacology . 347 . 5 . 453–463 . May 1993 . 7686633 . 10.1007/bf00166735 . 22129922 .
4. Book: van Wijngaarden I, Soudijn W, Tulp MT . 5-HT_1A Receptors . Soudijn W, Olivier B, van Wijngaarden I . Serotonin Receptors and Their Ligands . Elsevier . Amsterdam . 1997 . 0-444-82041-8 . https://books.google.com/books?id=lfo0hGqIex0C&pg=PA37.