| Termas de Río Hondo | |
| Native Name Lang: | es |
| Settlement Type: | City |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Termas de Río Hondo in Argentina |
| Coordinates: | -27.4833°N -116°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Type2: | Department |
| Subdivision Name2: | Río Hondo |
| Unit Pref: | Metric |
| Elevation M: | 265 |
| Population Total: | 32,116 |
| Population As Of: | 2010 census |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | −03:00 |
| Postal Code Type: | CPA base |
| Postal Code: | G4220 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3858 |
| Blank Name: | Climate |
| Blank Info: | Cwa |
Termas de Río Hondo is a spa city in Santiago del Estero Province, Argentina. It has 27,838 inhabitants as per the . It is located on the banks of the Dulce River, 65 km north of the provincial capital Santiago del Estero, near the artificial Río Hondo Lake.
The hot springs (Spanish: termas, Quechua: yacu rupaj) of the area have a temperature of over 30 °C (86 °F), and have made the town a popular spa resort for Argentines, who enjoy the waters recommended against high blood pressure and rheumatism. Two public pools, La Olla and the Pileta Municipal, are near the town centre, along with many well-regarded hotels and restaurants.
New investments done in the last years were the new Las Termas Airport and Autódromo Termas de Río Hondo, totally rebuilt to host MotoGP World Championship racing starting from April 2014.[1]
The town was on the route of the 2015 and 2016 Dakar Rally.